In the Hot Seat: John Mulaney & Nick Kroll / Kenan Thompson & Kel Mitchell

In the Hot Seat: Rosie O'Donnell & Lisa Ann Walter / Sebastian Maniscalco & Omar J. Dorsey

In the Hot Seat: Nicole Byer & Sasheer Zamata / John Stamos & Dave Coulier

In the Hot Seat: Sophia Bush & Alex Edelman / Jeff Ross & Jimmy's Cousin Sal

In the Hot Seat: “Lil Dicky” Dave Burd & GaTa / Kelly Osbourne & Jack Osbourne

In the Hot Seat: Ray Romano & Brad Garrett / Jason Ritter & Natasha Leggero

In the Hot Seat: Reggie Watts & Ron Funches / Gillian Jacobs & Danny Pudi